The Science of Joy: How IVF is Redefining Motherhood


IVF success rates in India normally vary between 30% and 35%, whereas the global average is approximately 40% for young women

IVF success rates in India normally vary between 30% and 35%, whereas the global average is approximately 40% for young women

Dr G Poornima, Consultant, Ferty9 Fertility Center discusses about how IVF is changing the landscape of motherhood

In the realm of assisted reproduction, the journey towards motherhood has witnessed remarkable scientific strides, offering newfound hope to individuals navigating the intricate maze of infertility. In vitro fertilization (IVF), once a pioneering technique, has evolved into a sophisticated field brimming with innovative technologies and methodologies.

  1. CryopreservationCryopreservation stands as a pivotal progress, granting individuals the option to preserve reproductive potential for future endeavours. Oocyte cryopreservation, commonly known as egg freezing, emerges as a beacon of hope for women seeking to postpone conception without compromising fertility. Moreover, it serves as a lifeline for individuals facing conditions such as ovarian cancer, safeguarding their reproductive options amidst the rigors of chemotherapy and radiation therapy. Cryopreservation is also offered to existing patients to store their excess embryos. If the ongoing cycle fails, the couple can vitrify the stored embryos and choose to take another cycle.
  2. Blastocyst CultivationBlastocyst cultivation and transfer is a specialised technique in in vitro fertilization (IVF) where the embryo is cultured to blastocyst, before transferring it into the womb. This method increases the likelihood of successful implantation because the embryo’s development stage aligns with the uterus conditions. Equipped with this step, patients can undergo single embryo transfer, lowering the chance of having multiple pregnancies.
  3. Physiological Intracytoplasmic Sperm Injection (PICSI)PICSI helps pick out the strongest sperm for fertilizing the egg during IVF. It does this by selecting sperm based on how well they stick to the hyaluronan around the egg. These chosen sperm are similar to the ones that would naturally succeed in fertilizing an egg. PICSI is especially recommended for those who’ve had past IVF failures, low fertilization rates even with ICSI, poor embryo quality or development issues not linked to egg quality, and repeated miscarriages.
  4. Preimplantation Genetic Testing (PGT)When an embryo transfer doesn’t lead to pregnancy, often it’s because of abnormal embryo genetics. Preimplantation genetic testing (PGT) ensures that only embryos with the genetically normal embryos are chosen for transfer, reducing IVF failure and miscarriage risks. Also, certain single gene disorders like cystic fibrosis, sickle cell anaemia, or blood disorders like thalassemia can be prevented by genetic testing, ensuring the transferred embryos don’t carry these conditions, which could be passed to the child.
  5. Assisted HatchingThe assisted hatching technique exemplifies the delicate art of embryo manipulation, wherein a minute opening is created in the embryo’s outer layer to enhance implantation potential. By fine-tuning this intricate process, embryologists augment the likelihood of successful pregnancy, ushering in a new era of hope and possibility. This technique is particularly beneficial for individuals with thick zona pellucida or advanced maternal age, where embryo implantation may be compromised.
  6. Integrative SupportBeyond individual advancements, the integration of state-of-the-art technologies such as K-System Incubators and the XILTRIX Alarm System ensures optimal conditions for embryo development, underlining a commitment to excellence in assisted reproduction. These inventive systems provide precise control over environmental parameters such as temperature, humidity, pH and gas composition, thereby streamlining embryo culture conditions and enhancing overall treatment outcomes.

Addressing the emotional stress: Psychological counselling plays a crucial role in the IVF journey by offering support before, during, and after treatments. Starting with the societal unacceptance around infertility to failed cycles, there are several emotional challenges to overcome during the treatment. Even after a successful birth, in many cases the physiological and psychological toll pushes IVF mothers into post-partum depression. Counselling helps manage stress, which can affect hormone levels and reproductive outcomes. It equips couples with coping strategies, fostering emotional strength to navigate the challenges of infertility treatment effectively.

Through relentless innovation and unwavering commitment, IVF is not merely reshaping the landscape of motherhood but also illuminating the path towards a future filled with boundless joy and potential. As we continue to push the boundaries of scientific discovery, the pursuit of parenthood is imbued with renewed optimism, empowering individuals to overcome infertility challenges and embrace the transformative quest towards creating a family.


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